Above All Psychedelic-Assisted Therapy Company is a clinical practice in Oklahoma City specializing in ketamine-assisted therapy (KAT) and psilocybin-assisted treatment for treatment-resistant depression, anxiety, PTSD, and chronic pain. The practice operates within Oklahoma's current legal and regulatory framework for ketamine, offering medically supervised infusions and guided therapeutic sessions designed to work alongside traditional talk therapy and medication management.
Psychedelic-assisted therapy differs fundamentally from standard counseling or psychiatric medication alone. The clinic administers controlled doses of ketamine or psilocybin in a clinical setting while a therapist or psychiatrist is present, with the goal of inducing a state of neuroplasticity that can make talk therapy more effective for conditions that have not responded to conventional treatment. Ketamine infusions are FDA-approved off-label for this use; psilocybin remains in clinical research protocols in Oklahoma and requires enrollment in an IRB-approved study. The business operates as an outpatient clinic, not a psychiatric hospital or inpatient facility, making it accessible to people who work or have family responsibilities and cannot take extended medical leave.
Above All offers ketamine-assisted therapy as the primary available service. A typical course involves 6 to 8 infusion sessions scheduled 2 to 3 times per week, with each infusion lasting approximately 40 minutes to an hour, followed by a 30 to 60 minute integration therapy session. Cost ranges from approximately $500 to $750 per infusion session, depending on dosage and whether therapy is bundled. A full course can total $3,000 to $6,000 depending on frequency and provider rates; confirm current pricing directly as rates can vary by insurance acceptance and promotional periods. Initial consultations typically cost $150 to $300 and may or may not be credited toward treatment if the patient proceeds. Some insurance plans cover off-label ketamine therapy, though coverage is inconsistent; patients should verify their plan's stance before booking. Psilocybin-assisted therapy is offered only through research enrollment, which is free but requires meeting strict clinical criteria and potential waitlisting.
Oklahoma City has limited psychedelic-assisted therapy providers. Several psychiatric practices, including those affiliated with OU Health and Integris, offer ketamine infusions in a more medically focused setting without the integrated therapy component, making them suitable for patients who prefer to work with their own therapist or want infusion-only treatment. Above All's distinguishing factor is the co-located therapeutic support during and after infusions, which aligns with research showing that ketamine's effectiveness increases when paired with active therapy in real time. Traditional psychiatrists in Oklahoma City typically prescribe SSRIs, SNRIs, and other medications with waits of 1 to 3 months for first appointments; ketamine-assisted therapy can produce faster symptom relief but requires commitment to multiple sessions over weeks. Therapists using standard evidence-based modalities such as cognitive-behavioral therapy or trauma-focused CBT remain the starting point for most insured patients and are considerably cheaper per visit ($80 to $200), but do not access the neuroplastic window that psychedelic compounds can open.
Above All is suited to patients with treatment-resistant depression, defined as depression that has not responded to at least two adequate trials of antidepressant medication, and to patients with PTSD, chronic pain syndromes, or anxiety who have tried standard medication and therapy without relief. It works well for people who can commit to 2 to 3 visits per week for 6 to 8 weeks and who are willing to tolerate dissociative side effects during infusions (feeling detached from the body or time, visual distortions). It is not suitable for patients with active psychosis, uncontrolled bipolar disorder, unmedicated substance use disorders, or certain cardiac conditions; the clinic conducts medical screening to rule these out. Patients on stimulants or other medications that interact with ketamine will need adjustments before treatment. Those seeking quick relief with minimal time commitment may find the frequency and duration burdensome compared to medication alone.
The initial consultation is a clinical intake, typically lasting 60 to 90 minutes, during which a psychiatrist or clinical staff member reviews psychiatric history, current medications, medical conditions, substance use, and reasons for seeking psychedelic-assisted therapy. They perform cardiac and cognitive screening, discuss the mechanism of ketamine therapy and its side effects, and review the clinic's consent process. If the patient is deemed medically safe and clinically appropriate, a treatment plan is outlined and a start date is scheduled. Some clinics ask patients to journal or identify a specific therapeutic goal before the first infusion. Patients are instructed not to eat for several hours before infusions and to arrange transportation home, as they cannot drive immediately after treatment.
Hours and exact parking arrangements vary by clinic location within Oklahoma City; confirm details directly when calling to schedule. Infusions typically run during business hours, Monday through Friday, with some clinics offering weekend or early-morning slots. Sessions run 90 minutes to 2 hours total (infusion plus therapy), and the clinic should have private waiting and recovery areas. Many Oklahoma City outpatient psychiatric clinics include street or lot parking; ask about accessibility if mobility is a concern.
Above All serves a real clinical gap in Oklahoma City for patients whose depression, anxiety, and PTSD have persisted through conventional treatment, offering a medically supervised pathway to compounds shown in controlled research to reduce symptoms faster than medication alone.
